USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: Q14353 USC-OGP 2-DE database:  Q14353 Q14353 General information about the entry View entry in simple text format Entry name GAMT_HUMAN Primary accession number Q14353 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Guanidinoacetate N-methyltransferase; EC=2.1.1.2;. Gene name Name=GAMT Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0789: pI=5.74; Mw=29960 Cross-references UniProtKB/Swiss-Prot Q14353; GAMT_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name GAMT_HUMAN Primary accession number Q14353 Secondary accession number(s) A8K0A0 Q53Y34 Q8WVJ1 Sequence was last modified on  November 1, 1996 (version 1) Annotations were last modified on  March 15, 2017 (version 164) Name and origin of the protein Description RecName: Full=Guanidinoacetate N-methyltransferase; EC=2.1.1.2; Gene name Name=GAMT Encoded on Name=GAMT Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Disease mutation; Methyltransferase; Polymorphism; Reference proteome; S-adenosyl-L-methionine; Transferase. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL Z49878; CAA90035.1; -; mRNA EMBL AF010248; AAD04781.1; -; Genomic_DNA EMBL AF010246; AAD04781.1; JOINED; Genomic_DNA EMBL AF010247; AAD04781.1; JOINED; Genomic_DNA EMBL AF188893; AAF01461.1; -; Genomic_DNA EMBL BT007034; AAP35682.1; -; mRNA EMBL AK289465; BAF82154.1; -; mRNA EMBL AC005329; AAC27668.1; -; Genomic_DNA EMBL CH471139; EAW69505.1; -; Genomic_DNA EMBL BC016760; AAH16760.1; -; mRNA EMBL BC017936; AAH17936.1; -; mRNA CCDS CCDS12064.1; -. [Q14353-1]; . CCDS CCDS45897.1; -. [Q14353-2]; . PIR S62732; S62732; . RefSeq NP_000147.1; NM_000156.5. [Q14353-1]; . RefSeq NP_620279.1; NM_138924.2. [Q14353-2]; . UniGene Hs.81131; -; . PDB 3ORH; X-ray; 1.86 A; A/B/C/D=1-236 PDBsum 3ORH; -; . ProteinModelPortal Q14353; -; . SMR Q14353; -; . BioGrid 108865; 8; . IntAct Q14353; 6; . STRING 9606.ENSP00000403536; -; . DrugBank DB00148; Creatine; . DrugBank DB00536; Guanidine; . DrugBank DB02751; N-[Amino(Imino)Methyl]Glycine; . DrugBank DB01752; S-Adenosyl-L-Homocysteine; . iPTMnet Q14353; -; . PhosphoSitePlus Q14353; -; . BioMuta GAMT; -; . DMDM 2498404; -; . OGP Q14353; -; . EPD Q14353; -; . PaxDb Q14353; -; . PeptideAtlas Q14353; -; . PRIDE Q14353; -; . DNASU 2593; -; . Ensembl ENST00000252288; ENSP00000252288; ENSG00000130005. [Q14353-1]; . Ensembl ENST00000447102; ENSP00000403536; ENSG00000130005. [Q14353-2]; . GeneID 2593; -; . KEGG hsa:2593; -; . UCSC uc002lsk.5; human. [Q14353-1]; . CTD 2593; -; . DisGeNET 2593; -; . GeneCards GAMT; -; . GeneReviews GAMT; -; . H-InvDB HIX0030201; -; . HGNC HGNC:4136; GAMT; . HPA HPA051806; -; . MalaCards GAMT; -; . MIM 601240; gene; . MIM 612736; phenotype; . neXtProt NX_Q14353; -; . OpenTargets ENSG00000130005; -; . Orphanet 382; Guanidinoacetate methyltransferase deficiency; . PharmGKB PA28549; -; . eggNOG KOG1709; Eukaryota; . eggNOG ENOG4110T2S; LUCA; . GeneTree ENSGT00390000018061; -; . HOGENOM HOG000010290; -; . HOVERGEN HBG005801; -; . InParanoid Q14353; -; . KO K00542; -; . OMA RYYAFPQ; -; . OrthoDB EOG091G0EPW; -; . PhylomeDB Q14353; -; . TreeFam TF328555; -; . BioCyc MetaCyc:HS05327-MONOMER; -; . BRENDA 2.1.1.2; 2681; . Reactome R-HSA-71288; Creatine metabolism; . UniPathway UPA00104; UER00580; . EvolutionaryTrace Q14353; -; . GeneWiki Guanidinoacetate_N-methyltransferase; -; . GenomeRNAi 2593; -; . PRO PR:Q14353; -; . Proteomes UP000005640; Chromosome 19; . Bgee ENSG00000130005; -; . CleanEx HS_GAMT; -; . ExpressionAtlas Q14353; baseline and differential; . Genevisible Q14353; HS; . GO GO:0005737; C:cytoplasm; IBA:GO_Central; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005634; C:nucleus; IBA:GO_Central; . GO GO:0030731; F:guanidinoacetate N-methyltransferase activity; IMP:UniProtKB; . GO GO:0008168; F:methyltransferase activity; TAS:Reactome; . GO GO:0009887; P:animal organ morphogenesis; IEA:Ensembl; . GO GO:0006601; P:creatine biosynthetic process; IDA:UniProtKB; . GO GO:0006600; P:creatine metabolic process; TAS:Reactome; . GO GO:0006936; P:muscle contraction; TAS:ProtInc; . GO GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl; . GO GO:0046498; P:S-adenosylhomocysteine metabolic process; IBA:GO_Central; . GO GO:0046500; P:S-adenosylmethionine metabolic process; IBA:GO_Central; . GO GO:0007283; P:spermatogenesis; IEA:Ensembl; . Gene3D 3.40.50.150; -; 1; . InterPro IPR016550; GuanidinoAc_N-MeTrfase; . InterPro IPR026480; RMT2_dom; . InterPro IPR029063; SAM-dependent_MTases; . PIRSF PIRSF009285; GAMT; 1; . SUPFAM SSF53335; SSF53335; 1; . PROSITE PS51559; SAM_RMT2; 1; .

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